BDBM13824 1-[(3-carbamimidoylphenyl)methyl]-3-chloro-N-(naphthalen-1-ylmethyl)-1H-indole-2-carboxamide::3-amidinobenzylindole carboxamide 8

SMILES: NC(=N)c1cccc(Cn2c(C(=O)NCc3cccc4ccccc34)c(Cl)c3ccccc23)c1

InChI Key: InChIKey=RAILUPZTMRJAKW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13824 (1-[(3-carbamimidoylphenyl)methyl]-3-chloro-N-(naph...) Show SMILES NC(=N)c1cccc(Cn2c(C(=O)NCc3cccc4ccccc34)c(Cl)c3ccccc23)c1 Show InChI InChI=1S/C28H23ClN4O/c29-25-23-13-3-4-14-24(23)33(17-18-7-5-10-20(15-18)27(30)31)26(25)28(34)32-16-21-11-6-9-19-8-1-2-12-22(19)21/h1-15H,16-17H2,(H3,30,31)(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	304	-8.88	n/a	n/a	n/a	n/a	n/a	7.8	25
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 45: 2749-69 (2002) Article DOI: 10.1021/jm0111346 BindingDB Entry DOI: 10.7270/Q27H1GTW
					More data for this Ligand-Target Pair