BDBM13842 1-[(3-carbamimidoylphenyl)methyl]-N-[2-(3,4-dichlorophenyl)ethyl]-4-hydroxy-1H-indole-2-carboxamide::3-amidinobenzylindole carboxamide 26

SMILES: NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCCc2ccc(Cl)c(Cl)c2)c1

InChI Key: InChIKey=CHROGWSHBDHTME-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13842 (1-[(3-carbamimidoylphenyl)methyl]-N-[2-(3,4-dichlo...) Show SMILES NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCCc2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C25H22Cl2N4O2/c26-19-8-7-15(12-20(19)27)9-10-30-25(33)22-13-18-21(5-2-6-23(18)32)31(22)14-16-3-1-4-17(11-16)24(28)29/h1-8,11-13,32H,9-10,14H2,(H3,28,29)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	918	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 45: 2749-69 (2002) Article DOI: 10.1021/jm0111346 BindingDB Entry DOI: 10.7270/Q27H1GTW
					More data for this Ligand-Target Pair