BDBM13858 1-[(3-carbamimidoylphenyl)methyl]-N-(3,5-dichlorophenyl)-4-hydroxy-1H-indole-2-carboxamide::3-amidinobenzylindole carboxamide 42::CHEMBL308510

SMILES: NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)Nc2cc(Cl)cc(Cl)c2)c1

InChI Key: InChIKey=FPRKQCJSMUAPDV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13858 (1-[(3-carbamimidoylphenyl)methyl]-N-(3,5-dichlorop...) Show SMILES NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)Nc2cc(Cl)cc(Cl)c2)c1 Show InChI InChI=1S/C23H18Cl2N4O2/c24-15-8-16(25)10-17(9-15)28-23(31)20-11-18-19(5-2-6-21(18)30)29(20)12-13-3-1-4-14(7-13)22(26)27/h1-11,30H,12H2,(H3,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	798	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Curated by ChEMBL					Assay Description Inhibitory activity against serine protease factor Xa (fXa) was determined				Bioorg Med Chem Lett 11: 227-30 (2001) BindingDB Entry DOI: 10.7270/Q2KD1X68
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM13858 (1-[(3-carbamimidoylphenyl)methyl]-N-(3,5-dichlorop...) Show SMILES NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)Nc2cc(Cl)cc(Cl)c2)c1 Show InChI InChI=1S/C23H18Cl2N4O2/c24-15-8-16(25)10-17(9-15)28-23(31)20-11-18-19(5-2-6-21(18)30)29(20)12-13-3-1-4-14(7-13)22(26)27/h1-11,30H,12H2,(H3,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	798	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 45: 2749-69 (2002) Article DOI: 10.1021/jm0111346 BindingDB Entry DOI: 10.7270/Q27H1GTW
					More data for this Ligand-Target Pair