BDBM138585 US8877741, 1.63

SMILES: CC(C)c1cccc(n1)N1CCC(C1)Oc1ccc(cc1)[C@H](C)NC(C)=O

InChI Key: InChIKey=OYXIOEIPXKSTHR-DJZRFWRSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 138585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (Homo sapiens (Human))	BDBM138585 (US8877741, 1.63) Show SMILES CC(C)c1cccc(n1)N1CCC(C1)Oc1ccc(cc1)[C@H](C)NC(C)=O |r| Show InChI InChI=1S/C22H29N3O2/c1-15(2)21-6-5-7-22(24-21)25-13-12-20(14-25)27-19-10-8-18(9-11-19)16(3)23-17(4)26/h5-11,15-16,20H,12-14H2,1-4H3,(H,23,26)/t16-,20?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8877741 (2014) BindingDB Entry DOI: 10.7270/Q2R78CXJ
					More data for this Ligand-Target Pair