BDBM13860 1-[(3-carbamimidoylphenyl)methyl]-N-[(3,5-dimethoxyphenyl)methyl]-4-hydroxy-1H-indole-2-carboxamide::3-amidinobenzylindole carboxamide 44

SMILES: COc1cc(CNC(=O)c2cc3c(O)cccc3n2Cc2cccc(c2)C(N)=N)cc(OC)c1

InChI Key: InChIKey=IDZYCWBZDALJHR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13860 (1-[(3-carbamimidoylphenyl)methyl]-N-[(3,5-dimethox...) Show SMILES COc1cc(CNC(=O)c2cc3c(O)cccc3n2Cc2cccc(c2)C(N)=N)cc(OC)c1 Show InChI InChI=1S/C26H26N4O4/c1-33-19-10-17(11-20(12-19)34-2)14-29-26(32)23-13-21-22(7-4-8-24(21)31)30(23)15-16-5-3-6-18(9-16)25(27)28/h3-13,31H,14-15H2,1-2H3,(H3,27,28)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	193	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 45: 2749-69 (2002) Article DOI: 10.1021/jm0111346 BindingDB Entry DOI: 10.7270/Q27H1GTW
					More data for this Ligand-Target Pair