BDBM138734 US8877741, 2.60

SMILES: C[C@H](NC(=O)C(F)F)c1ccc(OC2CCN(C2)c2ccc(OCC3CC3(F)F)cn2)cc1

InChI Key: InChIKey=ONYMAGUNQZMDCR-ASFAAARLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 138734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM138734 (US8877741, 2.60) Show SMILES C[C@H](NC(=O)C(F)F)c1ccc(OC2CCN(C2)c2ccc(OCC3CC3(F)F)cn2)cc1 |r| Show InChI InChI=1S/C23H25F4N3O3/c1-14(29-22(31)21(24)25)15-2-4-17(5-3-15)33-19-8-9-30(12-19)20-7-6-18(11-28-20)32-13-16-10-23(16,26)27/h2-7,11,14,16,19,21H,8-10,12-13H2,1H3,(H,29,31)/t14-,16?,19?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8877741 (2014) BindingDB Entry DOI: 10.7270/Q2R78CXJ
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