BDBM138743 US8877741, 2.69::US8877741, 2.76
SMILES: C[C@H](NC(=O)c1cnn(C)c1Cl)c1ccc(OC2CCN(C2)c2ccnc(OCC3CC3)c2)cc1
InChI Key: InChIKey=MNHUERDNCXYXAW-LBOXEOMUSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human)) | BDBM138743 (US8877741, 2.69 | US8877741, 2.76) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 24 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki... | US Patent US8877741 (2014) BindingDB Entry DOI: 10.7270/Q2R78CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human)) | BDBM138743 (US8877741, 2.69 | US8877741, 2.76) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 281 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki... | US Patent US8877741 (2014) BindingDB Entry DOI: 10.7270/Q2R78CXJ | |||||||||||
More data for this Ligand-Target Pair |