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SMILES: COC(=O)c1cccc(CNC(=O)c2cc3c(O)cccc3n2Cc2cccc(c2)C(N)=N)c1

InChI Key: InChIKey=CMQOCVCCCMZPAD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13879   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM13879
PNG
(3-amidinobenzylindole carboxamide 64 | methyl 3-[(...)
Show SMILES COC(=O)c1cccc(CNC(=O)c2cc3c(O)cccc3n2Cc2cccc(c2)C(N)=N)c1
Show InChI InChI=1S/C26H24N4O4/c1-34-26(33)19-8-2-5-16(11-19)14-29-25(32)22-13-20-21(9-4-10-23(20)31)30(22)15-17-6-3-7-18(12-17)24(27)28/h2-13,31H,14-15H2,1H3,(H3,27,28)(H,29,32)
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Similars
Article
PubMed
 2.04E+3n/an/an/an/an/an/an/an/a



Aventis Pharma Deutschland GmbH



Assay Description
The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...

J Med Chem 45: 2749-69 (2002)


Article DOI: 10.1021/jm0111346
BindingDB Entry DOI: 10.7270/Q27H1GTW
More data for this
Ligand-Target Pair