BDBM138928 US8877741, 9.64

SMILES: CCCOc1cc(ccn1)N1CC[C@H](C1)Oc1ccc(cc1)[C@H](C)NC(=O)c1cncs1

InChI Key: InChIKey=VCZZGIPWLREZOR-LAUBAEHRSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 138928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM138928 (US8877741, 9.64) Show SMILES CCCOc1cc(ccn1)N1CC[C@H](C1)Oc1ccc(cc1)[C@H](C)NC(=O)c1cncs1 |r| Show InChI InChI=1S/C24H28N4O3S/c1-3-12-30-23-13-19(8-10-26-23)28-11-9-21(15-28)31-20-6-4-18(5-7-20)17(2)27-24(29)22-14-25-16-32-22/h4-8,10,13-14,16-17,21H,3,9,11-12,15H2,1-2H3,(H,27,29)/t17-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8877741 (2014) BindingDB Entry DOI: 10.7270/Q2R78CXJ
					More data for this Ligand-Target Pair