BDBM139303 US8614223, 81
SMILES: ONC(=O)c1cnc(NC2(CC2)c2ccc(F)cc2)nc1
InChI Key: InChIKey=SDOJRNSWDIQVEP-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM139303 (US8614223, 81) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 47 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Acetylon Pharmaceuticals, Inc. US Patent | Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were... | US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM139303 (US8614223, 81) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Acetylon Pharmaceuticals, Inc. US Patent | Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were... | US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 3 (Homo sapiens (Human)) | BDBM139303 (US8614223, 81) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Acetylon Pharmaceuticals, Inc. US Patent | Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were... | US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 2 (Homo sapiens (Human)) | BDBM139303 (US8614223, 81) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 78 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Acetylon Pharmaceuticals, Inc. US Patent | Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were... | US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00 | |||||||||||
More data for this Ligand-Target Pair |