BDBM139445 US8889671, 55

SMILES: C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2[C@@H](COC2=O)c2ccccn2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=ISYLVRUSGYTPNY-QMERHICCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139445   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Gyrase Subunit A (Escherichia coli (strain K12))	BDBM139445 (US8889671, 55) Show SMILES C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2[C@@H](COC2=O)c2ccccn2)C(=O)NC(=O)NC1=O |r| Show InChI InChI=1S/C26H23FN6O7/c1-11-9-32-18-13(8-26(20(32)12(2)39-11)22(34)29-24(36)30-23(26)35)7-14-19(17(18)27)40-31-21(14)33-16(10-38-25(33)37)15-5-3-4-6-28-15/h3-7,11-12,16,20H,8-10H2,1-2H3,(H2,29,30,34,35,36)/t11-,12+,16+,20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...				US Patent US8889671 (2014) BindingDB Entry DOI: 10.7270/Q22J69JX
					More data for this Ligand-Target Pair