BDBM139474 US8889672, 317-052-001

SMILES: COc1ccc(cc1OC)-c1csc(N)c1C(=O)OCc1ccccc1F

InChI Key: InChIKey=RHHMMDZTAHYGJS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C zeta type (Homo sapiens (Human))	BDBM139474 (US8889672, 317-052-001) Show SMILES COc1ccc(cc1OC)-c1csc(N)c1C(=O)OCc1ccccc1F Show InChI InChI=1S/C20H18FNO4S/c1-24-16-8-7-12(9-17(16)25-2)14-11-27-19(22)18(14)20(23)26-10-13-5-3-4-6-15(13)21/h3-9,11H,10,22H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; The Penn State Research Foundation US Patent					Assay Description IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...				US Patent US8889672 (2014) BindingDB Entry DOI: 10.7270/Q2T43RS0
					More data for this Ligand-Target Pair