BDBM139513 US8889708, 11

SMILES: Fc1cc(ccc1C#N)-c1ccc(C[C@H](NC(=O)C23CCC(CC2)N3)C#N)cc1

InChI Key: InChIKey=GKQJTUJNAOVIAL-KQVJYAISSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139513   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM139513 (US8889708, 11) Show SMILES Fc1cc(ccc1C#N)-c1ccc(C[C@H](NC(=O)C23CCC(CC2)N3)C#N)cc1 |r| Show InChI InChI=1S/C23H21FN4O/c24-21-12-17(5-6-18(21)13-25)16-3-1-15(2-4-16)11-20(14-26)27-22(29)23-9-7-19(28-23)8-10-23/h1-6,12,19-20,28H,7-11H2,(H,27,29)/t19?,20-,23?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	284	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...				US Patent US8889708 (2014) BindingDB Entry DOI: 10.7270/Q2JM28BB
					More data for this Ligand-Target Pair