BDBM139651 US8894989, 30
SMILES: O=c1[nH]nc2[nH]c(CN3CCN(CC3)c3ccccn3)nc3cccc1c23
InChI Key: InChIKey=WKFCDYTXJLAJAM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM139651 (US8894989, 30) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Eisai Inc. US Patent | Assay Description A convenient method to determine IC50 of a PARP inhibitor compound is a PARP assay using purified recombinant human PARP from Trevigan (Gaithersburg,... | US Patent US8894989 (2014) BindingDB Entry DOI: 10.7270/Q21J98GF | |||||||||||
More data for this Ligand-Target Pair |