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SMILES: COc1ccccc1C1CCCN1C(=O)CNC(=O)NCc1ccc(N)nc1

InChI Key: InChIKey=BHPWTAFLPJBPHI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140000   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptidyl-prolyl cis-trans isomerase B


(Homo sapiens (Human))		BDBM140000
PNG
(US8901295, F587)
Show SMILES COc1ccccc1C1CCCN1C(=O)CNC(=O)NCc1ccc(N)nc1
Show InChI InChI=1S/C20H25N5O3/c1-28-17-7-3-2-5-15(17)16-6-4-10-25(16)19(26)13-24-20(27)23-12-14-8-9-18(21)22-11-14/h2-3,5,7-9,11,16H,4,6,10,12-13H2,1H3,(H2,21,22)(H2,23,24,27)
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US Patent
n/an/a 5.20E+3n/an/an/an/a7.820



Institut National de la Sante et de la Recherche Medicale (INSERM); Universite Montpellier 1; Universite Paris-EST Creteil val de Marne; Assistance Publique-Hopitaux de Paris; Centre National de la Recherche Scientifique

US Patent


Assay Description
Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...

US Patent US8901295 (2014)


BindingDB Entry DOI: 10.7270/Q2R49PGS
More data for this
Ligand-Target Pair