BDBM140005 US8901295, F684
SMILES: CSc1ccccc1C1CCCN1C(=O)CNC(=O)NCc1ccc(N)cc1
InChI Key: InChIKey=BWOIOAFNMATNEP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclophilin A (CYPA) (Homo sapiens (Human)) | BDBM140005 (US8901295, F684) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 370 | n/a | n/a | n/a | n/a | 7.8 | 20 |
Institut National de la Sante et de la Recherche Medicale (INSERM); Universite Montpellier 1; Universite Paris-EST Creteil val de Marne; Assistance Publique-Hopitaux de Paris; Centre National de la Recherche Scientifique US Patent | Assay Description Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,... | US Patent US8901295 (2014) BindingDB Entry DOI: 10.7270/Q2R49PGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclophilin D (CypD) (Homo sapiens (Human)) | BDBM140005 (US8901295, F684) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 640 | n/a | n/a | n/a | n/a | 7.8 | 20 |
Institut National de la Sante et de la Recherche Medicale (INSERM); Universite Montpellier 1; Universite Paris-EST Creteil val de Marne; Assistance Publique-Hopitaux de Paris; Centre National de la Recherche Scientifique US Patent | Assay Description Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,... | US Patent US8901295 (2014) BindingDB Entry DOI: 10.7270/Q2R49PGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclophilin B (CypB) (Homo sapiens (Human)) | BDBM140005 (US8901295, F684) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 650 | n/a | n/a | n/a | n/a | 7.8 | 20 |
Institut National de la Sante et de la Recherche Medicale (INSERM); Universite Montpellier 1; Universite Paris-EST Creteil val de Marne; Assistance Publique-Hopitaux de Paris; Centre National de la Recherche Scientifique US Patent | Assay Description Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,... | US Patent US8901295 (2014) BindingDB Entry DOI: 10.7270/Q2R49PGS | |||||||||||
More data for this Ligand-Target Pair |