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SMILES: CC(C)COC(=O)O[C@@]1(CC[C@]2(Cc3ccccc3)[C@H](CCc3cc(ccc23)C(=O)Nc2cccnc2C)C1)C(F)(F)F

InChI Key: InChIKey=AGYBPLZBQKCDOK-UKOABYEESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140021   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM140021
PNG
(US8901310, Comparator K)
Show SMILES CC(C)COC(=O)O[C@@]1(CC[C@]2(Cc3ccccc3)[C@H](CCc3cc(ccc23)C(=O)Nc2cccnc2C)C1)C(F)(F)F |r|
Show InChI InChI=1S/C34H37F3N2O4/c1-22(2)21-42-31(41)43-33(34(35,36)37)16-15-32(19-24-8-5-4-6-9-24)27(20-33)13-11-25-18-26(12-14-28(25)32)30(40)39-29-10-7-17-38-23(29)3/h4-10,12,14,17-18,22,27H,11,13,15-16,19-21H2,1-3H3,(H,39,40)/t27-,32+,33-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
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Similars
US Patent
n/an/a 895n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...

US Patent US8901310 (2014)


BindingDB Entry DOI: 10.7270/Q2MC8XQM
More data for this
Ligand-Target Pair