BDBM141039 US8916576, 267
SMILES: Oc1ccc2nc(nc(Nc3ccc4[nH]ncc4c3)c2c1)-c1ccccc1
InChI Key: InChIKey=ABUYXWHKWYVATB-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM141039 (US8916576, 267) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Surface Logix, Inc. US Patent | Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.). | US Patent US8916576 (2014) BindingDB Entry DOI: 10.7270/Q2P55M6K | |||||||||||
More data for this Ligand-Target Pair |