BDBM141184 US8653100, 95

SMILES: CCCS(=O)(=O)NCCOc1ccc2CCNC(c2c1)C1(CCC1)c1cccc(F)c1

InChI Key: InChIKey=LEEGLBMDJSUWBA-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM141184 (US8653100, 95) Show SMILES CCCS(=O)(=O)NCCOc1ccc2CCNC(c2c1)C1(CCC1)c1cccc(F)c1 Show InChI InChI=1S/C24H31FN2O3S/c1-2-15-31(28,29)27-13-14-30-21-8-7-18-9-12-26-23(22(18)17-21)24(10-4-11-24)19-5-3-6-20(25)16-19/h3,5-8,16-17,23,26-27H,2,4,9-15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9
					More data for this Ligand-Target Pair
Glycine transporter 1 (Homo sapiens (Human))	BDBM141184 (US8653100, 95) Show SMILES CCCS(=O)(=O)NCCOc1ccc2CCNC(c2c1)C1(CCC1)c1cccc(F)c1 Show InChI InChI=1S/C24H31FN2O3S/c1-2-15-31(28,29)27-13-14-30-21-8-7-18-9-12-26-23(22(18)17-21)24(10-4-11-24)19-5-3-6-20(25)16-19/h3,5-8,16-17,23,26-27H,2,4,9-15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description [3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c_5_CHO cells were plated at 20,000 ...				US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9
					More data for this Ligand-Target Pair