BDBM141313 US8653257, 11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine
SMILES: C1CN(CCN1)C1=Nc2ccccc2Sc2ccccc12
InChI Key: InChIKey=JLOAJISUHPIQOX-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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D(2) dopamine receptor (Homo sapiens (Human)) | BDBM141313 (US8653257, 11-Piperazin-1-yl-dibenzo[b,f][1,4]thia...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Astrazeneca AB US Patent | Assay Description The ability of test compounds to displace 3H-raclopride at the D2s receptor can be determined on membranes from D2s-transfected CHO cells (Bmax 13 pm... | US Patent US8653257 (2014) BindingDB Entry DOI: 10.7270/Q2DR2T69 | |||||||||||
More data for this Ligand-Target Pair |