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SMILES: CCN(CC)CCSc1ccc(\C=C\C(=O)NO)cc1NC(=O)C(Cl)Cl

InChI Key: InChIKey=FDYCCWDPHWOAPH-SOFGYWHQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141913   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 6


(Homo sapiens (Human))		BDBM141913
PNG
(US8921424, 13)
Show SMILES CCN(CC)CCSc1ccc(\C=C\C(=O)NO)cc1NC(=O)C(Cl)Cl
Show InChI InChI=1S/C17H23Cl2N3O3S/c1-3-22(4-2)9-10-26-14-7-5-12(6-8-15(23)21-25)11-13(14)20-17(24)16(18)19/h5-8,11,16,25H,3-4,9-10H2,1-2H3,(H,20,24)(H,21,23)/b8-6+
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Similars
US Patent
n/an/a 313n/an/an/an/an/an/a



Zhejiang Hisun Pharmaceutical Co. Ltd.; Central South University

US Patent


Assay Description
The BIOMOL fluorescent-based HDAC activity assay has been applied in In vitro HDACi assay for determination of IC50 values of the compounds of this i...

US Patent US8921424 (2014)


BindingDB Entry DOI: 10.7270/Q2BR8QWP
More data for this
Ligand-Target Pair