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SMILES: Cc1cc(C)c(CNC(=O)n2sc3ncccc3c2=O)c(C)c1

InChI Key: InChIKey=AGJUWPUELJLDNW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142064   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))		BDBM142064
PNG
(US8933024, 29)
Show SMILES Cc1cc(C)c(CNC(=O)n2sc3ncccc3c2=O)c(C)c1
Show InChI InChI=1S/C17H17N3O2S/c1-10-7-11(2)14(12(3)8-10)9-19-17(22)20-16(21)13-5-4-6-18-15(13)23-20/h4-8H,9H2,1-3H3,(H,19,22)
KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 4.29E+3n/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...

US Patent US8933024 (2015)


BindingDB Entry DOI: 10.7270/Q228069H
More data for this
Ligand-Target Pair