BDBM142065 US8933024, 37

SMILES: COc1ccc(cc1OC)C(C)NC(=O)n1sc2ncccc2c1=O

InChI Key: InChIKey=LTXBHPWMOKGCHN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM142065 (US8933024, 37) Show SMILES COc1ccc(cc1OC)C(C)NC(=O)n1sc2ncccc2c1=O Show InChI InChI=1S/C17H17N3O4S/c1-10(11-6-7-13(23-2)14(9-11)24-3)19-17(22)20-16(21)12-5-4-8-18-15(12)25-20/h4-10H,1-3H3,(H,19,22)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...				US Patent US8933024 (2015) BindingDB Entry DOI: 10.7270/Q228069H
					More data for this Ligand-Target Pair