BDBM142073 US8933024, 115

SMILES: COc1cc(CNC(=O)n2sc3ncccc3c2=O)ccc1OCCN(C)C

InChI Key: InChIKey=QSKCWNCYXQRWQM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM142073 (US8933024, 115) Show SMILES COc1cc(CNC(=O)n2sc3ncccc3c2=O)ccc1OCCN(C)C Show InChI InChI=1S/C19H22N4O4S/c1-22(2)9-10-27-15-7-6-13(11-16(15)26-3)12-21-19(25)23-18(24)14-5-4-8-20-17(14)28-23/h4-8,11H,9-10,12H2,1-3H3,(H,21,25)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...				US Patent US8933024 (2015) BindingDB Entry DOI: 10.7270/Q228069H
					More data for this Ligand-Target Pair