BDBM142074 US8933024, 116

SMILES: CC(C)Oc1ncccc1CNC(=O)n1sc2ncccc2c1=O

InChI Key: InChIKey=TWRSGEXZNYNUAP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM142074 (US8933024, 116) Show SMILES CC(C)Oc1ncccc1CNC(=O)n1sc2ncccc2c1=O Show InChI InChI=1S/C16H16N4O3S/c1-10(2)23-13-11(5-3-7-17-13)9-19-16(22)20-15(21)12-6-4-8-18-14(12)24-20/h3-8,10H,9H2,1-2H3,(H,19,22)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...				US Patent US8933024 (2015) BindingDB Entry DOI: 10.7270/Q228069H
					More data for this Ligand-Target Pair