BDBM142076 US8933024, 130

SMILES: CN(C)Cc1ccc(CNC(=O)n2sc3ncccc3c2=O)cc1

InChI Key: InChIKey=OJUJWPJNAURRHV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM142076 (US8933024, 130) Show SMILES CN(C)Cc1ccc(CNC(=O)n2sc3ncccc3c2=O)cc1 Show InChI InChI=1S/C17H18N4O2S/c1-20(2)11-13-7-5-12(6-8-13)10-19-17(23)21-16(22)14-4-3-9-18-15(14)24-21/h3-9H,10-11H2,1-2H3,(H,19,23)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...				US Patent US8933024 (2015) BindingDB Entry DOI: 10.7270/Q228069H
					More data for this Ligand-Target Pair