BDBM142077 US8933024, 134

SMILES: CC(NC(=O)n1sc2ncccc2c1=O)c1ccc(cc1)N1CCOCC1

InChI Key: InChIKey=AORPAILDQYOXEW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM142077 (US8933024, 134) Show SMILES CC(NC(=O)n1sc2ncccc2c1=O)c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C19H20N4O3S/c1-13(14-4-6-15(7-5-14)22-9-11-26-12-10-22)21-19(25)23-18(24)16-3-2-8-20-17(16)27-23/h2-8,13H,9-12H2,1H3,(H,21,25)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	391	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...				US Patent US8933024 (2015) BindingDB Entry DOI: 10.7270/Q228069H
					More data for this Ligand-Target Pair