BDBM142078 US8933024, 142

SMILES: COCCN1CCC(CNC(=O)n2sc3ncccc3c2=O)CC1

InChI Key: InChIKey=UVZNDUSUJATZHW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142078   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM142078 (US8933024, 142) Show SMILES COCCN1CCC(CNC(=O)n2sc3ncccc3c2=O)CC1 Show InChI InChI=1S/C16H22N4O3S/c1-23-10-9-19-7-4-12(5-8-19)11-18-16(22)20-15(21)13-3-2-6-17-14(13)24-20/h2-3,6,12H,4-5,7-11H2,1H3,(H,18,22)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	517	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...				US Patent US8933024 (2015) BindingDB Entry DOI: 10.7270/Q228069H
					More data for this Ligand-Target Pair