BDBM142080 US8933024, 161

SMILES: COCCOc1ccc(cc1OC)[C@@H](C)NC(=O)n1sc2ncccc2c1=O

InChI Key: InChIKey=JKYHGSIBUKOQJC-GFCCVEGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM142080 (US8933024, 161) Show SMILES COCCOc1ccc(cc1OC)[C@@H](C)NC(=O)n1sc2ncccc2c1=O |r| Show InChI InChI=1S/C19H21N3O5S/c1-12(13-6-7-15(16(11-13)26-3)27-10-9-25-2)21-19(24)22-18(23)14-5-4-8-20-17(14)28-22/h4-8,11-12H,9-10H2,1-3H3,(H,21,24)/t12-/m1/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...				US Patent US8933024 (2015) BindingDB Entry DOI: 10.7270/Q228069H
					More data for this Ligand-Target Pair