BDBM142326 US8933099, 92

SMILES: CCN1CCC(CC1)c1ccc(cc1)C(=O)Nc1cc(Oc2cc3ccn(C(=O)NC)c3cc2OCCOC)ccn1

InChI Key: InChIKey=ODHGIFQCKBHAPS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM142326 (US8933099, 92) Show SMILES CCN1CCC(CC1)c1ccc(cc1)C(=O)Nc1cc(Oc2cc3ccn(C(=O)NC)c3cc2OCCOC)ccn1 Show InChI InChI=1S/C32H37N5O5/c1-4-36-14-10-23(11-15-36)22-5-7-24(8-6-22)31(38)35-30-20-26(9-13-34-30)42-29-19-25-12-16-37(32(39)33-2)27(25)21-28(29)41-18-17-40-3/h5-9,12-13,16,19-21,23H,4,10-11,14-15,17-18H2,1-3H3,(H,33,39)(H,34,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	25
Eisai R&D Management Co., Ltd. US Patent					Assay Description In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR1 protein is measured.To each well of a flat b...				US Patent US8933099 (2015) BindingDB Entry DOI: 10.7270/Q28S4NMG
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