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SMILES: Cc1cccc(N2CCN(CC2)c2nc(cc(=O)n2C)-c2ncncc2F)c1C

InChI Key: InChIKey=FDLAIOLJTJUIHP-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142851   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microtubule-associated protein tau


(Bos taurus (Bovine))		BDBM142851
PNG
(US8940738, 7)
Show SMILES Cc1cccc(N2CCN(CC2)c2nc(cc(=O)n2C)-c2ncncc2F)c1C
Show InChI InChI=1S/C21H23FN6O/c1-14-5-4-6-18(15(14)2)27-7-9-28(10-8-27)21-25-17(11-19(29)26(21)3)20-16(22)12-23-13-24-20/h4-6,11-13H,7-10H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

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AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 78.3n/an/an/an/a6.525



Mitsubishi Tanabe Pharma Corporation

US Patent


Assay Description
A mixture containing 100 mM MES-sodium hydroxide (pH 6.5), 1 mM magnesium acetate, 0.5 mM EGTA, 5 mM beta-mercaptoethanol, 0.02% Tween 20, 10% glycer...

US Patent US8940738 (2015)


BindingDB Entry DOI: 10.7270/Q2M32TG6
More data for this
Ligand-Target Pair