BDBM14302 benzthiazole analog 5::benzyl N-[(2S)-3-(6-aminopyridin-3-yl)-1-(1,3-benzothiazol-2-yl)-1-oxopropan-2-yl]carbamate

SMILES: Nc1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)c2nc3ccccc3s2)cn1

InChI Key: InChIKey=KIVCNEUHAVTBFW-SFHVURJKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsin (Bos taurus (bovine))	BDBM14302 (benzthiazole analog 5 | benzyl N-[(2S)-3-(6-aminop...) Show SMILES Nc1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)c2nc3ccccc3s2)cn1 |r| Show InChI InChI=1S/C23H20N4O3S/c24-20-11-10-16(13-25-20)12-18(27-23(29)30-14-15-6-2-1-3-7-15)21(28)22-26-17-8-4-5-9-19(17)31-22/h1-11,13,18H,12,14H2,(H2,24,25)(H,27,29)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera					Assay Description Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...				Biochemistry 45: 5964-73 (2006) Article DOI: 10.1021/bi060173m BindingDB Entry DOI: 10.7270/Q2W09450
					More data for this Ligand-Target Pair
Tryptase (Homo sapiens (Human))	BDBM14302 (benzthiazole analog 5 | benzyl N-[(2S)-3-(6-aminop...) Show SMILES Nc1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)c2nc3ccccc3s2)cn1 |r| Show InChI InChI=1S/C23H20N4O3S/c24-20-11-10-16(13-25-20)12-18(27-23(29)30-14-15-6-2-1-3-7-15)21(28)22-26-17-8-4-5-9-19(17)31-22/h1-11,13,18H,12,14H2,(H2,24,25)(H,27,29)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.50E+5	>-5.16	n/a	n/a	n/a	n/a	n/a	7.4	22
Celera					Assay Description Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...				Biochemistry 45: 5964-73 (2006) Article DOI: 10.1021/bi060173m BindingDB Entry DOI: 10.7270/Q2W09450
					More data for this Ligand-Target Pair