BDBM14304 benzthiazole analog 7::benzyl N-[(2S)-3-(3-amino-1H-indazol-5-yl)-1-(1,3-benzothiazol-2-yl)-1-oxopropan-2-yl]carbamate

SMILES: Nc1n[nH]c2ccc(C[C@H](NC(=O)OCc3ccccc3)C(=O)c3nc4ccccc4s3)cc12

InChI Key: InChIKey=ZFASOOPFBLQFOQ-FQEVSTJZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsin (Bos taurus (bovine))	BDBM14304 (benzthiazole analog 7 | benzyl N-[(2S)-3-(3-amino-...) Show SMILES Nc1n[nH]c2ccc(C[C@H](NC(=O)OCc3ccccc3)C(=O)c3nc4ccccc4s3)cc12 |r| Show InChI InChI=1S/C25H21N5O3S/c26-23-17-12-16(10-11-18(17)29-30-23)13-20(28-25(32)33-14-15-6-2-1-3-7-15)22(31)24-27-19-8-4-5-9-21(19)34-24/h1-12,20H,13-14H2,(H,28,32)(H3,26,29,30)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera					Assay Description Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...				Biochemistry 45: 5964-73 (2006) Article DOI: 10.1021/bi060173m BindingDB Entry DOI: 10.7270/Q2W09450
					More data for this Ligand-Target Pair
Tryptase (Homo sapiens (Human))	BDBM14304 (benzthiazole analog 7 | benzyl N-[(2S)-3-(3-amino-...) Show SMILES Nc1n[nH]c2ccc(C[C@H](NC(=O)OCc3ccccc3)C(=O)c3nc4ccccc4s3)cc12 |r| Show InChI InChI=1S/C25H21N5O3S/c26-23-17-12-16(10-11-18(17)29-30-23)13-20(28-25(32)33-14-15-6-2-1-3-7-15)22(31)24-27-19-8-4-5-9-21(19)34-24/h1-12,20H,13-14H2,(H,28,32)(H3,26,29,30)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.50E+5	>-5.16	n/a	n/a	n/a	n/a	n/a	7.4	22
Celera					Assay Description Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...				Biochemistry 45: 5964-73 (2006) Article DOI: 10.1021/bi060173m BindingDB Entry DOI: 10.7270/Q2W09450
					More data for this Ligand-Target Pair