null

SMILES: OC(=O)c1ccc(CNc2ncnc3ccc(cc23)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=HDBLJKNAWUHBNB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 143633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM143633 (US9682955, 60) Show SMILES OC(=O)c1ccc(CNc2ncnc3ccc(cc23)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C29H21Cl2N3O2/c30-23-10-5-19(6-11-23)27(20-7-12-24(31)13-8-20)22-9-14-26-25(15-22)28(34-17-33-26)32-16-18-1-3-21(4-2-18)29(35)36/h1-15,17,27H,16H2,(H,35,36)(H,32,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	27
Janssen Pharmaceutica NV US Patent					Assay Description The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...				US Patent US9682955 (2017) BindingDB Entry DOI: 10.7270/Q2707ZM3
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM143633 (US9682955, 60) Show SMILES OC(=O)c1ccc(CNc2ncnc3ccc(cc23)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C29H21Cl2N3O2/c30-23-10-5-19(6-11-23)27(20-7-12-24(31)13-8-20)22-9-14-26-25(15-22)28(34-17-33-26)32-16-18-1-3-21(4-2-18)29(35)36/h1-15,17,27H,16H2,(H,35,36)(H,32,33,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	27
Janssen Pharmaceutica NV US Patent					Assay Description The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...				US Patent US9682955 (2017) BindingDB Entry DOI: 10.7270/Q2707ZM3
					More data for this Ligand-Target Pair