BDBM143818 US8969325, 19

SMILES: Cn1c2cccc(NC(=O)N[C@@H]3CC(C)(C)Oc4cc(F)ccc34)c2ccc1=O

InChI Key: InChIKey=GFRDOUNRVDHWKR-QGZVFWFLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 143818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM143818 (US8969325, 19) Show SMILES Cn1c2cccc(NC(=O)N[C@@H]3CC(C)(C)Oc4cc(F)ccc34)c2ccc1=O Show InChI InChI=1S/C22H22FN3O3/c1-22(2)12-17(15-8-7-13(23)11-19(15)29-22)25-21(28)24-16-5-4-6-18-14(16)9-10-20(27)26(18)3/h4-11,17H,12H2,1-3H3,(H2,24,25,28)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...				US Patent US8969325 (2015) BindingDB Entry DOI: 10.7270/Q29P30BX
					More data for this Ligand-Target Pair