BDBM144211 US8969335, A36
SMILES: N#Cc1cc(ccc1OC1CCOCC1)-c1ccnc(Nc2ncc3CNCCc3n2)c1
InChI Key: InChIKey=VVSBXDVZQDKKTO-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (Homo sapiens (Human)) | BDBM144211 (US8969335, A36) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 140 | n/a | n/a | n/a | n/a | 7.5 | 30 |
MERCK PATENT GmbH US Patent | Assay Description 1 nM IKKe, 800 nM biotinylated IkBalpha(19-42) peptide (Biotin-C6-C6-GLKKERLLDDRHDSGLDSMKDEE) and 10 μM ATP (spiked with 0.3 uCi of 33P-ATP/well) ar... | US Patent US8969335 (2015) BindingDB Entry DOI: 10.7270/Q25X27NN | |||||||||||
More data for this Ligand-Target Pair |