BDBM144236 US8952008, 29

SMILES: COc1cc(ccc1-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CCC1)S(C)(=O)=O

InChI Key: InChIKey=WAOBWKDFKARWAM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144236 (US8952008, 29) Show SMILES COc1cc(ccc1-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CCC1)S(C)(=O)=O Show InChI InChI=1S/C23H21FN4O3S/c1-31-21-11-16(32(2,29)30)7-8-17(21)18-10-14(6-9-20(18)24)19-12-26-27-23-22(19)25-13-28(23)15-4-3-5-15/h6-13,15H,3-5H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair