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SMILES: OC(=O)C(c1ccccc1)n1nc(Cc2cccc3ccccc23)c2ccccc2c1=O

InChI Key: InChIKey=VEJXCOIVBQLOOM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144343   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chymase


(Homo sapiens (Human))		BDBM144343
PNG
(US8969348, [4-(Naphthalen-1-ylmethyl)-1-oxophthala...)
Show SMILES OC(=O)C(c1ccccc1)n1nc(Cc2cccc3ccccc23)c2ccccc2c1=O
Show InChI InChI=1S/C27H20N2O3/c30-26-23-16-7-6-15-22(23)24(17-20-13-8-12-18-9-4-5-14-21(18)20)28-29(26)25(27(31)32)19-10-2-1-3-11-19/h1-16,25H,17H2,(H,31,32)
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Similars
US Patent
n/an/a 170n/an/an/an/a8.0n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....

US Patent US8969348 (2015)


BindingDB Entry DOI: 10.7270/Q2J38R8B
More data for this
Ligand-Target Pair