BDBM144477 US8969568, 28

SMILES: COc1cc(cc(OC)c1OC)-c1cc2ncccc2c(OCC2CC(=O)NO2)n1

InChI Key: InChIKey=HCNHJMCOTOMFJM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM144477 (US8969568, 28) Show SMILES COc1cc(cc(OC)c1OC)-c1cc2ncccc2c(OCC2CC(=O)NO2)n1 Show InChI InChI=1S/C21H21N3O6/c1-26-17-7-12(8-18(27-2)20(17)28-3)15-10-16-14(5-4-6-22-16)21(23-15)29-11-13-9-19(25)24-30-13/h4-8,10,13H,9,11H2,1-3H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	67.1	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH & Co. KG US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US8969568 (2015) BindingDB Entry DOI: 10.7270/Q2154FRD
					More data for this Ligand-Target Pair