BDBM144505 US8969568, 58

SMILES: O=C1C[C@@H](COc2nc(cc3ncccc23)-c2ccc3OCOc3c2)CN1

InChI Key: InChIKey=SNTVFXQUZVZQIW-GFCCVEGCSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM144505 (US8969568, 58) Show SMILES O=C1C[C@@H](COc2nc(cc3ncccc23)-c2ccc3OCOc3c2)CN1 |r| Show InChI InChI=1S/C20H17N3O4/c24-19-6-12(9-22-19)10-25-20-14-2-1-5-21-16(14)8-15(23-20)13-3-4-17-18(7-13)27-11-26-17/h1-5,7-8,12H,6,9-11H2,(H,22,24)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15.3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH & Co. KG US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US8969568 (2015) BindingDB Entry DOI: 10.7270/Q2154FRD
					More data for this Ligand-Target Pair