BDBM144583 US8969578, 18

SMILES: OP(O)(=O)Oc1ccc(Cc2sc(nc2C(=O)Nc2ccc(cc2)C2CCCCC2)-c2cccc3ccccc23)cc1

InChI Key: InChIKey=KONBXYHYCFRQKA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM144583 (US8969578, 18) Show SMILES OP(O)(=O)Oc1ccc(Cc2sc(nc2C(=O)Nc2ccc(cc2)C2CCCCC2)-c2cccc3ccccc23)cc1 Show InChI InChI=1S/C33H31N2O5PS/c36-32(34-26-17-15-24(16-18-26)23-7-2-1-3-8-23)31-30(21-22-13-19-27(20-14-22)40-41(37,38)39)42-33(35-31)29-12-6-10-25-9-4-5-11-28(25)29/h4-6,9-20,23H,1-3,7-8,21H2,(H,34,36)(H2,37,38,39)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Central Florida Research Foundation, Inc. US Patent					Assay Description A screening process evaluated in vitro disruption of STAT3(dimer)-DNA formation through a previously published EMSA based assays, giving a valuable i...				US Patent US8969578 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z84
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