BDBM145379 US8952169, 158

SMILES: CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCC3(CC3)CC2)cc1F

InChI Key: InChIKey=KLIKOKNVYOMZPS-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 145379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM145379 (US8952169, 158) Show SMILES CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCC3(CC3)CC2)cc1F Show InChI InChI=1S/C20H26FNO4S/c1-27(24,25)22-19(23)16-10-15(14-2-3-14)18(11-17(16)21)26-12-13-4-6-20(7-5-13)8-9-20/h10-11,13-14H,2-9,12H2,1H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	25
Xenon Pharmaceuticals Inc.; Genentech, Inc. US Patent					Assay Description Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...				US Patent US8952169 (2015) BindingDB Entry DOI: 10.7270/Q2M04445
					More data for this Ligand-Target Pair