BDBM147141 US8957077, 1-13

SMILES: CC(C[C@@H]1C[C@H]1c1ccccn1)c1cc(NCc2sc(C)nc2C)n2nccc2n1

InChI Key: InChIKey=OMKOLDKFPQMPHA-KNHHTTPFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM147141 (US8957077, 1-13) Show SMILES CC(C[C@@H]1C[C@H]1c1ccccn1)c1cc(NCc2sc(C)nc2C)n2nccc2n1 |r| Show InChI InChI=1S/C23H26N6S/c1-14(10-17-11-18(17)19-6-4-5-8-24-19)20-12-23(29-22(28-20)7-9-26-29)25-13-21-15(2)27-16(3)30-21/h4-9,12,14,17-18,25H,10-11,13H2,1-3H3/t14?,17-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	76.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exper...				US Patent US8957077 (2015) BindingDB Entry DOI: 10.7270/Q29G5KHW
					More data for this Ligand-Target Pair