BDBM147414 US8957093, 252

SMILES: C[C@H](NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1ccccc1C

InChI Key: InChIKey=HIZJHEWINJXBHY-QHCPKHFHSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 147414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM147414 (US8957093, 252) Show SMILES C[C@H](NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1ccccc1C |r| Show InChI InChI=1S/C34H32N2O3/c1-21-9-5-6-10-28(21)23(3)35-33(37)27-17-18-32-31(19-27)22(2)24(4)36(32)20-25-13-15-26(16-14-25)29-11-7-8-12-30(29)34(38)39/h5-19,23H,20H2,1-4H3,(H,35,37)(H,38,39)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute US Patent					Assay Description The assay was performed according to manufacturer protocol. A mixture of nM GST-PPARG-LBD, 5 nM Tb-GST-antibody, 5 nM Fluormone Pan-PPAR Green, and s...				US Patent US8957093 (2015) BindingDB Entry DOI: 10.7270/Q2X63KNR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM147414 (US8957093, 252) Show SMILES C[C@H](NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1ccccc1C |r| Show InChI InChI=1S/C34H32N2O3/c1-21-9-5-6-10-28(21)23(3)35-33(37)27-17-18-32-31(19-27)22(2)24(4)36(32)20-25-13-15-26(16-14-25)29-11-7-8-12-30(29)34(38)39/h5-19,23H,20H2,1-4H3,(H,35,37)(H,38,39)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Binding affinity to GST-tagged PPAR-gamma-LBD (unknown origin) after 2 hrs by Lantha screen assay using fluormone Pan-PPAR green probe				ACS Med Chem Lett 6: 998-1003 (2015) Article DOI: 10.1021/acsmedchemlett.5b00218 BindingDB Entry DOI: 10.7270/Q29026SZ
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM147414 (US8957093, 252) Show SMILES C[C@H](NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1ccccc1C |r| Show InChI InChI=1S/C34H32N2O3/c1-21-9-5-6-10-28(21)23(3)35-33(37)27-17-18-32-31(19-27)22(2)24(4)36(32)20-25-13-15-26(16-14-25)29-11-7-8-12-30(29)34(38)39/h5-19,23H,20H2,1-4H3,(H,35,37)(H,38,39)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	147	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Transactivation of human PPARgamma in HEK293T cells after 18 hrs by luciferase reporter gene assay				ACS Med Chem Lett 6: 998-1003 (2015) Article DOI: 10.1021/acsmedchemlett.5b00218 BindingDB Entry DOI: 10.7270/Q29026SZ
					More data for this Ligand-Target Pair