null
SMILES: Cc1c(Cl)c(ccc1N1C(=S)N(CCCOc2ccc(-c3ccncc3)c(c2)C(F)(F)F)C(C)(C)C1=O)C#N
InChI Key: InChIKey=KEYRNTPQDWRGSM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (Mus musculus) | BDBM148293 (US9682960, EM-8820) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | 7.4 | 25 |
ENDORECHERCHE, INC. US Patent | Assay Description Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit... | US Patent US9682960 (2017) BindingDB Entry DOI: 10.7270/Q2PZ5708 | |||||||||||
More data for this Ligand-Target Pair |