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SMILES: Cc1c(Cl)c(ccc1N1C(=O)N(CCCOc2ccc(-c3cc[n+]([O-])cc3)c(c2)C(F)(F)F)C(C)(C)C1=O)C#N

InChI Key: InChIKey=YEEJQDVSAMLYLX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 148327   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen receptor


(Mus musculus)		BDBM148327
PNG
(US9682960, EM-9334)
Show SMILES Cc1c(Cl)c(ccc1N1C(=O)N(CCCOc2ccc(-c3cc[n+]([O-])cc3)c(c2)C(F)(F)F)C(C)(C)C1=O)C#N
Show InChI InChI=1S/C28H24ClF3N4O4/c1-17-23(8-5-19(16-33)24(17)29)36-25(37)27(2,3)35(26(36)38)11-4-14-40-20-6-7-21(22(15-20)28(30,31)32)18-9-12-34(39)13-10-18/h5-10,12-13,15H,4,11,14H2,1-3H3
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 29n/an/an/an/a7.425



ENDORECHERCHE, INC.

US Patent


Assay Description
Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...

US Patent US9682960 (2017)


BindingDB Entry DOI: 10.7270/Q2PZ5708
More data for this
Ligand-Target Pair