BDBM148722 US8962641, 8.79

SMILES: CCN(CC(F)(F)F)c1nccc(n1)N1CC[C@H](C1)Oc1ccc(cc1)[C@H](C)NC(C)=O

InChI Key: InChIKey=CRCFXZWNBFNQDS-HNAYVOBHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 148722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM148722 (US8962641, 8.79) Show SMILES CCN(CC(F)(F)F)c1nccc(n1)N1CC[C@H](C1)Oc1ccc(cc1)[C@H](C)NC(C)=O |r| Show InChI InChI=1S/C22H28F3N5O2/c1-4-29(14-22(23,24)25)21-26-11-9-20(28-21)30-12-10-19(13-30)32-18-7-5-17(6-8-18)15(2)27-16(3)31/h5-9,11,15,19H,4,10,12-14H2,1-3H3,(H,27,31)/t15-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8962641 (2015) BindingDB Entry DOI: 10.7270/Q2H130Q5
					More data for this Ligand-Target Pair