BDBM149283 US8962674, CU381

SMILES: Oc1ccc(c(\C=C\C(=O)CC(=O)\C=C\c2cc(O)ccc2[N+]([O-])=O)c1)[N+]([O-])=O

InChI Key: InChIKey=REOJVSQKHBGBSF-ZPUQHVIOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM149283 (US8962674, CU381) Show SMILES Oc1ccc(c(\C=C\C(=O)CC(=O)\C=C\c2cc(O)ccc2[N+]([O-])=O)c1)[N+]([O-])=O Show InChI InChI=1S/C19H14N2O8/c22-14-5-7-18(20(26)27)12(9-14)1-3-16(24)11-17(25)4-2-13-10-15(23)6-8-19(13)21(28)29/h1-10,22-23H,11H2/b3-1+,4-2+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	790	n/a	n/a	n/a	n/a	4.5	37
Tokyo Institute of Technology; Kyoto University US Patent					Assay Description Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...				US Patent US8962674 (2015) BindingDB Entry DOI: 10.7270/Q2QJ7G1J
					More data for this Ligand-Target Pair