BDBM149317 US8962674, CU530

SMILES: Oc1ccc(CCC(=O)CC(=O)\C=C\c2cc(O)ccc2[N+]([O-])=O)cc1

InChI Key: InChIKey=HYLYNRZZDOQOGG-XBXARRHUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM149317 (US8962674, CU530) Show SMILES Oc1ccc(CCC(=O)CC(=O)\C=C\c2cc(O)ccc2[N+]([O-])=O)cc1 Show InChI InChI=1S/C19H17NO6/c21-15-5-1-13(2-6-15)3-7-17(23)12-18(24)8-4-14-11-16(22)9-10-19(14)20(25)26/h1-2,4-6,8-11,21-22H,3,7,12H2/b8-4+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	600	n/a	n/a	n/a	n/a	4.5	37
Tokyo Institute of Technology; Kyoto University US Patent					Assay Description Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...				US Patent US8962674 (2015) BindingDB Entry DOI: 10.7270/Q2QJ7G1J
					More data for this Ligand-Target Pair