BDBM149341 US8962837, 37

SMILES: CC1CN(CCC1Oc1cc(ccc1Cl)C(F)(F)F)c1nccnn1

InChI Key: InChIKey=PFTDBWKSVBQWLD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149341 (US8962837, 37) Show SMILES CC1CN(CCC1Oc1cc(ccc1Cl)C(F)(F)F)c1nccnn1 Show InChI InChI=1S/C16H16ClF3N4O/c1-10-9-24(15-21-5-6-22-23-15)7-4-13(10)25-14-8-11(16(18,19)20)2-3-12(14)17/h2-3,5-6,8,10,13H,4,7,9H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair